Science at the Shine Dome 2010
Annual symposium: Genomics and mathematics
Genome-wide studies are often carried out today to identify connections between genomic features and observable traits.They are of interest to medical scientists and biologists because they can help identify the genomic components of diseases such as cancer. But they also challenge, and therefore fascinate, mathematical statisticians, not least because they involve many more 'features' (eg, genes or fragments of DNA) than there are independent sources of information (eg, people in a sample). While data on genomic variation clearly lie at the heart of this work, mathematical methods and computational algorithms for implementing them are needed to make sense of the data.
The symposium will bring together scientists working on both genomic and mathematical aspects of these problems, so that each area might learn about the progress of the other, and to identify new frontiers in this rapidly evolving area.
| Friday 7 May 2010 Symposium |
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| 8.45am | Welcome Professor Kurt Lambeck President, Australian Academy of Science |
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| 8.50am | Opening remarks Professor Peter Hall FAA |
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| 9.00am | Integrating science, technology, data and mathematics Professor Terry Speed FAA Bioinformatics, Walter and Eliza Hall Institute of Medical Research |
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| 9.30am | Chair: Professor Terry Speed Epigenetics and genetics: Discovery of layers of change in the cancer genome Professor Susan Clark Garvan Institute of Medical Research |
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| 10.25am | Morning tea | |||
| 10.50am | Chair: Dr Iain Johnstone Combining genomics and mathematics to learn about cancer Professor Simon Tavaré Department of Oncology, University of Cambridge |
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| 11.45am | Statistical analysis of quantitative proteomics analysis Dr Jean Yang School of Mathematics and Statistics, University of Sydney |
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| 12.15pm | Lunch | |||
| 1.20pm | Chair: Professor Susan Clark Constraint-based reconstruction and analysis of metabolic and regulatory networks Professor Lars Nielsen Biological Engineering, Australian Institute for Bioengineering and Nanotechnology |
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| 2.15pm | Studying cancer genomes at single nucleotide resolution Professor Sean Grimmond Institute for Molecular Bioscience, University of Queensland |
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| 2.45pm | Effects of network topology on the speed, synchrony and reliability of transcriptional regulation Professor Steven Evans Departments of Statistics and Mathematics, University of California, Berkeley |
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| 3.40pm | Afternoon tea | |||
| 4.05pm | Chair: Professor Peter Hall Extremes of variation in high-dimensional data Dr Iain Johnstone Department of Statistics, Stanford University |
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| 5.00pm | Closing remarks | |||
| Social program | ||||
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