Professor Gabrielle Belz is an immunologist whose work has provided seminal insights into cellular and molecular mechanisms that shape the immune system’s response to pathogen infections. Her work has uncovered the breadth of the responsiveness of anti-viral immune cells, the essential role of helper CD4 T cells in the generation of memory CD8 T cells and defined the antigen-presenting cells required for responses to pathogens and tissue-antigens. Her work has also uncovered how innate cells collaborate with adaptive cells in a key immune checkpoint. Professor Belz’s work has provided fundamental knowledge identifying new elements of the functioning of the immune system that could be harnessed therapeutically.